Molecular Wound

cost saving of incorporating precision life sciences
quickly manage skin and soft tissue infections precision life sciences

Quickly manage skin and soft tissue infections, avoid delays in diagnosis and prevent infections from progressing using Precision Life Sciences' comprehensive molecular wound panel. Precision's panel provides insight into 46 pathogens and 42 antibiotic-resistant genes.

According to the National Institutes of Health, chronic, nonhealing wounds impact about 8.2 million Medicare beneficiaries. Medicare cost projections for wounds range between $28.1 and $96.8 billion, including costs for infection management. Patients with infected wounds can experience an abnormal healing process that can lead to longer-term care, additional medications, and persisting pain; leading to lower activity, depression, irritation, and reduced social activity.

Classic culture methods do not completely depict microbial interactions or microorganisms within a wound. In contrast, PCR quantitatively represents all microorganisms contributing to these polymicrobial infections. Thus allowing clinicians to treat the primary organisms responsible for nonhealing wounds.

quickly manage skin and soft tissue infections precision life sciences

    • Prevents delays in diagnosis & treatment

    • Detects Polymicrobial infections

    • Unaffected concurrent medications

    • Reduces unnecessary drug exposure and adverse events

    • Decreases the progression and spread of infection

    • Improves selection of narrow-spectrum antibiotics

    • Prepares clinicians to make cost-sensitive treatment decisions

    • Easily accessible (web-portal or EHR integration)

    • Ability to provide antimicrobial stewardship monthly reports at request

    • Easy sample collection

    • Fast, accurate, comprehensive results (24 hours)

    • It helps reduce treatment failures

    • Access to scientific, clinical, and pharmaceutical support staff

Culture and Sensitivity vs. Molecular

The limitations of traditional culture techniques lead to increased treatment costs through a lack of antibiotic stewardship, longer treatment times, more invasive medical interventions, and a higher incidence of progressed complications. Mose importantly, this leads to increased pain and suffering.

99% of all infections are polymicrobial or bio/Hm, with high abundance levels. This means many different organisms are present in an infection or wound, contributing to the infected state. The challenge here is that many of these microorganisms are very different from each other and require special attention. A culture cannot grow a biofilm or even multiple organisms.

Cultural & Sensitivity

  • Sensitivity analysis can provide antibiotic MIC

  • Allows for quantization of bacterial population

  • 3-5 day turnaround time

  • Prone to mixed culture results

  • Results may limit antibiotic options

Molecular Based Diagnosis

  • 24-hour results

  • >95% Accuracy

  • >95% Sensitivity

  • >99% Specificity

  • Ease of use

  • Speciation easily identified

  • Can detect numerous individual entities in a biofilm without loss to culture

  • Antiobiotic recommendations for polymicrobial infections

Gram-Positive

  • S. aureus

  • S. epidermidis

  • Strep pyogenes

  • Strep agalactiae

  • Strep viridans

  • F. magna

  • C. perfringens

  • P. prevotti

  • P. acnes

  • E. faecafis

Gram-Negative

  • E.coli

  • 8. fragilis

  • K. pneumoniae

  • P. mirabilis

  • P. aeruginosa

  • A. baumanii

  • C. braakii

  • S. marcescens

Yeast

  • Candida albicans

  • Candida glabrata

  • Candida parapsilosis

  • Candida dubliniensis

  • Candida tropicalis